Kamis, 05 Januari 2012

tuberculosis disease


CHAPTER I
ANTECEDENT


1.1  Background
Most people know tuberculosis (TB) as a disease of the lungs. However, not all TB disease is in the lungs. Around 40% of TB disease occurs in another part of the body. This happens when the bacteria spread outside of the lungs. In these cases, TB is more difficult to diagnose since the patient does not have the normal signs and symptoms associated with pulmonary TB. TB disease can also occur in the lymph glands, brain, spine, kidneys, or other organs.
Tuberculosis is a respiratory disease that is passed to other people through coughing and sneezing over a period of time and where there is little ventilation to prevent it from spreading. At this point the bacteria enter their respiratory system and can spread to other organs if it is not suppressed by the person’s immune system. If the person who is exposed to TB is healthy, their immune system is then able to contain the bacteria and the person then has what is called Latent TB, which may become active if their immune system is somehow impaired, either by age or other diseases such as AIDS. When the person’s immune system takes over it is able to contain the bacteria in small sacs or tubercles in the lungs, thus preventing the bacteria from spreading to other parts of the body where it can cause much damage and even death. If for some reason the body isn’t able to stop the spreading of the disease then the bacteria would be spread through the blood to other parts of the body such as the spine, kidneys, and female reproductive organs. In addition a mother is able to spread it to her unborn child.
Once TB is spread through the body to other organs the bacteria are attacked by the immune system and a minor "war" is started and both sides lose "warriors." The bacteria die and also healthy tissues die and turn into growths that are called granulomas. The bacteria are able to live within these granulomas. However, they do cease growing.
It must be stated also that even though this disease is contagious, it is only the person’s respiratory system that is the method contagion; a person cannot get TB from touching the person or their bedding or clothing. So, while proper ventilation is quite necessary, avoiding touching the person or their clothing is not necessary at all. Touch remains a very healthy and necessary part of life and can sometimes assist in providing a person with emotional encouragement and peace in this and any other illness.
Left untreated, each person with active TB disease will infect on average between 10 and 15 people every year. But people infected with TB bacilli will not necessarily become sick with the disease. The immune system "walls off" the TB bacilli which, protected by a thick waxy coat, can lie dormant for years. When someone's immune system is weakened, the chances of becoming sick are greater.
-          Someone in the world is newly infected with TB bacilli every second.
-          Overall, one-third of the world's population is currently infected with the TB bacillus.
-          5-10% of people who are infected with TB bacilli (but who are not infected with HIV) become sick or infectious at some time during their life. People with HIV and TB infection are much more likely to develop TB.
When a person’s immune system is weakened and they are exposed to TB or have Latent TB then the disease becomes active. The bacteria then begin to war against the body, and destruction can be rather severe depending both on the level of the person’s immune system and the location of the bacteria. The respiratory system is the most common place where the bacteria grow. Respiratory symptoms may include horrible coughing that extends longer than three weeks, chest pains, blood or sputum when coughing. Other symptoms include extreme fatigue, reduced weight, loss of appetite, high fever, chills, night sweats.
Important nurse so central in TBC patient healing. Specially in medication, nurse as gift execution medicinize also the observation take medicine for the TBC patient. While family of playing a part in of progress from medication result and have to give motivation to family member incured by TBC in order to they the confidence will heal until the complete medication. Nurse of playing a part in to breathe life into at patient especially coming from it self family or through source or people trusted have influence to healing process and also own role in security requirement accomplishment earn the sharing directly and also indirectly. Directly the nurse can do conduct treatment upbringing of at client experiencing of related problem by not fullfiled is security requirement. As for nurse role in security requirement accomplishment is as direct treatment giver, educator that is give health education to family and client in order to the family and client do conduct related family health upbringing program with security requirement self-supportingly, and hold responsible to family security problem., health supervisor, consultant, kolaborasi, fasilitator, inventor problem, and the environmental modification ( Medical.Blogspot )
Pursuant to above background, hence the writer interested to do conduct research with an eye to can know about TBC desease, prevention and also medication and role of nurse in RS XX.

1.2  Problem formulation
From above background hence formula of problem of  this research is not yet been known by the TBC desease prevention.

1.3   Research Target
How to prevention of TBC disease and role of nurse of patient of TBC in RS. XX ?
1.4   Research Benefit
1.4.1        Common Target
 To know prevention and role of nurse [of] [at] patient tbc
 1.4.2 Special Target
1. To know TBC desease prevention
2. To know role of nurse of p



CHAPTER II
EVALUATE BOOK

2.1  Definition
Tuberculosis Disease (TB) is a very contagious disease of the respiratory system. It is a bacterial infection that begins in the lungs and is able to spread by the circulatory system to other parts of the body, such as the Meninges (the tissue covering the brain), spine, kidneys, and other abdominal organs and may be fatal. Tuberculosis symptoms are loss of appetite and weight, sweating at night, and fever.
Tuberculosis or TB is a common and often deadly infectious disease caused by various strains of mycobacteria, usually Mycobacterium tuberculosis in humans.Tuberculosis usually attacks the lungs but can also affect other parts of the body. It is spread through the air, when people who have the disease cough, sneeze, or spit.Most infections in humans result in an asymptomatic, latent infection, and about one in ten latent infections eventually progresses to active disease, which, if left untreated, kills more than 50% of its victims.
Tuberculosis is a respiratory disease that is passed to other people through coughing and sneezing over a period of time and where there is little ventilation to prevent it from spreading. At this point the bacteria enter their respiratory system and can spread to other organs if it is not suppressed by the person’s immune system. If the person who is exposed to TB is healthy, their immune system is then able to contain the bacteria and the person then has what is called Latent TB, which may become active if their immune system is somehow impaired, either by age or other diseases such as AIDS. When the person’s immune system takes over it is able to contain the bacteria in small sacs or tubercles in the lungs, thus preventing the bacteria from spreading to other parts of the body where it can cause much damage and even death. If for some reason the body isn’t able to stop the spreading of the disease then the bacteria would be spread through the blood to other parts of the body such as the spine, kidneys, and female reproductive organs. In addition a mother is able to spread it to her unborn child. Once TB is spread through the body to other organs the bacteria are attacked by the immune system and a minor "war" is started and both sides lose "warriors." The bacteria die and also healthy tissues die and turn into growths that are called granulomas. The bacteria are able to live within these granulomas. However, they do cease growing. It must be stated also that even though this disease is contagious, it is only the person’s respiratory system that is the method contagion; a person cannot get TB from touching the person or their bedding or clothing. So, while proper ventilation is quite necessary, avoiding touching the person or their clothing is not necessary at all. Touch remains a very healthy and necessary part of life and can sometimes assist in providing a person with emotional encouragement and peace in this and any other illness. Someone Latent TB is not contagious, asymptomatic (having no symptoms), feel healthy, however they do have a positive skin test and the tuberculosis get active without treatment for the Latent TB. In most cases this person never gets TB, the bacterium remaining inactive through the rest of their life.

2.2  Classification

The current clinical classification system for tuberculosis (TB) is based on the pathogenesis of the disease.
Classification System for TB
Class
Type
Description
0
No TB exposure
Not infected
No history of exposure
Negative reaction to tuberculin skin test
1
TB exposure
No evidence of infection
History of exposure
Negative reaction to tuberculin skin test
2
TB infection
No disease
Positive reaction to tuberculin skin test
Negative bacteriologic studies
No clinical, bacteriologic, or radiographic evidence of TB
3
TB, clinically active
M. tuberculosis cultured (if done)
Clinical, bacteriologic, or radiographic evidence of current disease
4
TB
Not clinically active
History of episode of TB or
Abnormal but stable radiographic findings
Positive reaction to the tuberculin skin test
Negative bacteriologic studies and
No clinical or radiographic evidence of current disease
5
TB suspect
Diagnosis pending
TB disease should be ruled in or out within 3 months

2.3  Signs and symptoms

When the disease becomes active, 75% of the cases are pulmonary TB, that is, TB in the lungs. Symptoms include chest pain , coughing up blood, and a productive, prolonged cough for more than three weeks. Systemic symptoms include fever, chills, night sweats, appetite loss, weight loss, pallor, and often a tendency to fatigue very easily. In the other 25% of active cases, the infection moves from the lungs, causing other kinds of TB, collectively denoted extrapulmonary tuberculosis.This occurs more commonly in immunosuppressed persons and young children. Extrapulmonary infection sites include the pleura in tuberculosis pleurisy, the central nervous system in meningitis, the lymphatic system in scrofula of the neck, the genitourinary system in urogenital tuberculosis, and bones and joints in Pott’s disease of the spine. An especially serious form is disseminated TB, more commonly known as ,military tuberculosis. Extrapulmonary TB may co-exist with pulmonary TB as well.

2.4   Causes Tuberculosis
When a person’s immune system is weakened and they are exposed to TB or have Latent TB then the disease becomes active. The bacteria then begin to war against the body, and destruction can be rather severe depending both on the level of the person’s immune system and the location of the bacteria. The respiratory system is the most common place where the bacteria grow.
Respiratory symptoms may include horrible coughing that extends longer than three weeks, chest pains, blood or sputum when coughing. Other symptoms include extreme fatigue, reduced weight, loss of appetite, high fever, chills, night sweats. In addition, TB results in abnormal chest x-rays and lab results. It also must be remembered that a person with active TB can spread it easily to others nearby. Adequate ventilation is a must. Also caution by those attending to or visiting the patient must be taken.

2.5   Risk Faktor
Persons with silicosis have an approximately 30-fold greater risk for developing TB. Silica particles irritate the respiratory system, causing immunogenic responses such as phagocytosis which consequently results in high lymphatic vessel deposits. It is this interference and blockage of macrophage function which increases the risk of tuberculosis. Persons with chronic renal failure who are on hemodialysis also have an increased risk: 10—25 times greater than the general population. Persons with diabetes mellitus have a risk for developing active TB that is two to four times greater than persons without diabetes mellitus, and this risk is likely greater in persons with insulin-dependent or poorly controlled diabetes. Other clinical conditions that have been associated with active TB include gastrectomy with attendant weight loss and malabsorption, jejunoileal bypass, renal and cardiac transplantation, carcinoma of the head or neck, and other neoplasms (e.g., lung cancer, lymphoma, and leukemia).
Given that silicosis greatly increases the risk of tuberculosis, more research about the effect of various indoor or outdoor air pollutants on the disease would be necessary. Some possible indoor source of silica includes paint, concrete and Portland cement. Crystalline silica is found in concrete, masonry, sandstone, rock, paint, and other abrasives. The cutting, breaking, crushing, drilling, grinding, or abrasive blasting of these materials may produce fine silica dust. It can also be in soil, mortar, plaster, and shingles. When you wear dusty clothing at home or in your car, you may be carrying silica dust that your family will breathe.
Low body weight is associated with risk of tuberculosis as well. A body mass index (BMI) below 18.5 increases the risk by 2—3 times. On the other hand, an increase in body weight lowers the risk. Patients with diabetes mellitus are at increased risk of contracting tuberculosis, and they have a poorer response to treatment, possibly due to poorer drug absorption
Some drugs, including rheumatoid arthritis drugs that work by blocking tumor necrosis factor-alpha (an inflammation-causing cytokine), raise the risk of activating a latent infection due to the importance of this cytokine in the immune defense against TB.

2.6   Prevention
TB prevention and control takes two parallel approaches. In the first, people with TB and their contacts are identified and then treated. Identification of infections often involves testing high-risk groups for TB. In the second approach, children are vaccinated to protect them from TB. No vaccine is available that provides reliable protection for adults. However, in tropical areas where the levels of other species of mycobacteria are high, exposure to nontubercolous mycobacteria gives some protection against TB.
The WHO declared TB a global health emergency in 1993, and the Stop TB Partnership developed a Global Plan to Stop Tubercolusis that aims to save 14 million lives between 2006 and 2015. Since humans are the only host of Mycobacterium tuberculosis, eradication would be possible. This goal would be helped greatly by an effective vaccine.
2.7  Treatment
Treatment for TB uses antibiotics to kill the bacteria. Effective TB treatment is difficult, due to the unusual structure and chemical composition of the mycobacterial cell wall, which makes many antibiotics ineffective and hinders the entry of drugs. The two antibiotics most commonly used are rifampicin and isoniazid. However, instead of the short course of antibiotics typically used to cure other bacterial infections, TB requires much longer periods of treatment (around 6 to 24 months) to entirely eliminate mycobacteria from the body. Latent TB treatment usually uses a single antibiotic, while active TB disease is best treated with combinations of several antibiotics, to reduce the risk of the bacteria developing antibiotic resistance. People with latent infections are treated to prevent them from progressing to active TB disease later in life.
Drug resistant tuberculosis is transmitted in the same way as regular TB. Primary resistance occurs in persons who are infected with a resistant strain of TB. A patient with fully susceptible TB develops secondary resistance (acquired resistance) during TB therapy because of inadequate treatment, not taking the prescribed regimen appropriately, or using low quality medication.Drug-resistant TB is a public health issue in many developing countries, as treatment is longer and requires more expensive drugs. Multi-drug-resistant tuberculosis (MDR-TB) is defined as resistance to the two most effective first-line TB drugs: rifampicin and isoniazid. Extesively drug-resistant TB (XDR-TB) is also resistant to three or more of the six classes of second-line drugs. The DOTS (Directly Observed Treatment Short-course) strategy of tuberculosis treatment recommended by WHO was based on clinical trials done in the 1970s by Tuberculosis Research Centre, Chennai, India. The country in which a person with TB lives can determine what treatment they receive. This is because multidrug-resistant tuberculosis is resistant to most first-line medications, the use second-line antituberculosis medications is necessary to cure the patient. However, the price of these medications is high; thus poor people in the developing world have no or limited access to these treatments.
2.8  Role of family and nurse
Specially in medication, nurse as gift execution medicinize also the observation take medicine for the TBC patient. While family of playing a part in of progress from medication result and have to give motivation to family member incured by TBC in order to they the confidence will heal until the complete medication. Nurse of playing a part in to breathe life into at patient especially coming from it self family or through source or people trusted have influence to healing process and also own role in security requirement accomplishment earn the sharing directly and also indirectly. Directly the nurse can do conduct treatment upbringing of at client experiencing of related problem by not fullfiled is security requirement. As for nurse role in security requirement accomplishment is as direct treatment giver, educator that is give health education to family and client in order to the family and client do conduct related family health upbringing program with security requirement self-supportingly, and hold responsible to family security problem., health supervisor, consultant, kolaborasi, fasilitator, inventor problem, and the environmental modification.


CHAPTER IV
CLOSING

Tuberculosis Disease (TB) is a very contagious disease of the respiratory system. It is a bacterial infection that begins in the lungs and is able to spread by the circulatory system to other parts of the body, such as the Meninges (the tissue covering the brain), spine, kidneys, and other abdominal organs and may be fatal. Tuberculosis symptoms are loss of appetite and weight, sweating at night, and fever.
TB prevention and control takes two parallel approaches. In the first, people with TB and their contacts are identified and then treated. Identification of infections often involves testing high-risk groups for TB. In the second approach, children are vaccinated to protect them from TB. No vaccine is available that provides reliable protection for adults. However, in tropical areas where the levels of other species of mycobacteria are high, exposure to nontubercolous mycobacteria gives some protection against TB.
Important nurse so central in TBC patient healing. Specially in medication, nurse as gift execution medicinize also the observation take medicine for the TBC patient.

Muttaqin, A. 2008. Asuhan Keperawatan dengan Gangguan Pernapasan. Jakarta: Salemba Medika

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